A simple model for configurations of DNA pt. I
Long charged polymers like DNA can be threaded through small constrictions by electric fields. This allows to study them, determine their size, or scan them during their passage. Interestingly, the configurations of the molecules when pushed into these constrictions can be modeled using a very simple Ising model. This recovers some well known results and produces suprising insights into the nanoscale behaviour these polymers get up to.
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Is plasmonic nanotweezing of single proteins possible?
Optical tweezing, using light to manipulate small objects, has revolutionized molecular biophysics as it allowed the study of proteins, the molecular workhorses, at the single-molecule level. Plasmonic nanotweezers are posed to further revolutionize this technology, but even over 15 years after their invention, they haven't delivered. Why is that?
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